http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2517757-A1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286
filingDate 2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2cdac36ea9c5a07dac405976c1c5830
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publicationDate 2004-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2517757-A1
titleOfInvention A method of preparing ligands for hydrophobic interaction chromatography
abstract The invention is a method of preparing multimodal ligands for hydrophobic interaction chromatography (HIC), which comprises providing a cyclic scaffold comprising a thiol, an amine and a carbonyl group; derivatisation of the nitrogen with a reagent to introduce a primary interaction; and aminolysis of the resulting derivative, whereby a secondary interaction is introduced next to the carbonyl; wherein at least one of the primary interaction and the secondary interaction comprises a hydrophobic group and wherein non of said interactions comprises charged groups, i.e. ion exchange ligands. The invention also encompasses a separation medium comprising such multimodal ligands immobilised to a base matrix.
priorityDate 2003-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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