| abstract |
The present invention relates to a process for the prevention or treatment of cardiovascular, cardiopulmonary, pulmonary or renal diseases by improving endothelial function and achieving protection of organs, tissues and blood vessels in indications in which control of blood pressure and lipid levels are necessary, particularly in people in whom type 2 diabetes mellitus has been diagnosed or who are suspected of prediabetes, for preventing diabetes and prediabetes, or for the treatment of Metabolic Syndrome and insulin resistance in patients with normal blood pressure. The process comprises generally administering effective amounts of telmisartan or a polymorph or salt thereof and simvastatin. The invention further relates to suitable pharmaceutical compositions which contain telmisartan or a polymorph or salt thereof and simvastatin, as a combined preparation for simultaneous, separate or sequential use in the prevention or treatment of these diseases. |