abstract |
The invention relates to compounds of general formula (I), in which R1 represents a piperazino, p-phenylendiamine, 2,5-diazabicyclo-2.2.1-heptane, 2,5-diazabicyclo-2.2.2-octane, or 3,8-diazabicyclo-3.2.1-octane residue, each of which can be substituted with at least one substituent, R2, R4, which are identical, represent a pyrrolidino, thiazolidine, oxazolidine, or imidazolidine residue, each of which can be substituted with at least one substituent, R3 represents an alkyl, alkoxy, alkylmercapto, or alkylamino residue, each of which can be substituted with at least one substituent, and the acid addition salts thereof. Said pteridine derivatives are suitable as phosphodiesterase inhibitors and therefore for the prophylaxis and/or therapy of thrombo-embolic, neuro-degenerating diseases, inflammatory diseases, asthmatic diseases, and hemato-oncological diseases. |