abstract |
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels and/or depressing cortical neuron activity. More particularly, the invention provides derivatives of N- phenylanthranilic acid or 2-benzimidazolone, compositions and methods that a re useful in the treatment of central or peripheral nervous system disorders an d as neuroprotective agents. |