| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2003-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4ffd97b6b0d1886d7e542c83683c3b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f251ca17fc87c8a31b0f1579380feb41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f61bee4f12568a611f36992e5ae525ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5b6ed40d16f268a87e17bd607601850
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41fa963d641b7ef390a7f62c8e4106f1 |
| publicationDate |
2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2502182-A1 |
| titleOfInvention |
Pyrimido[4,5-d]pyrimidine derivatives with anticancer activity |
| abstract |
Disclosed are novel pyrimido compounds of the formula (I) wherein R1 to R9 a re as defined in the specification, that are selective inhibitors of both KDR a n FGFR kinases and are selective against LCK. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in th e treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and the use for 10 treating cancer. |
| priorityDate |
2002-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |