http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2499536-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5db6243e0edb49c2d3e7af3f5580b7fd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
| filingDate | 2003-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bea7f8d33ce9f3bd0fb1a697329954c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9bb98ba52b64ffad3a42ecedab4c50d |
| publicationDate | 2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2499536-C |
| titleOfInvention | Method of preparing amino acid taxane derivatives and polymer conjugates containing the same |
| abstract | Methods of preparing amino acid-substituted taxanes such as: (see formula 4) using selected blocked amino acids are disclosed. After coupling of the blocked amino acid to the taxane, deprotection is carried out with about an equimolar amount of a secondary amine thus substantially avoiding base-catalyzed hydrolysis of amino acid from the taxane. The preferred amino acid-taxanes are useful as intermediates in the production of polymer conjugated therapeutic compositions or as part of pharmaceutically acceptable formulations. |
| priorityDate | 2002-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.