| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ac1d45776a8a24b24fec258548e537 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 |
| filingDate |
2003-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4322ba85e10c64d0159f0dad5d21a81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e576c9e83d1facfea15c8d8dddd957b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b409411d34b2a8791805383fc1c9e2f |
| publicationDate |
2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2490626-A1 |
| titleOfInvention |
Prodrug, medicinal utilization thereof and process for producing the same |
| abstract |
A prodrug with the use of an enzyme showing different enzymatic activities between a drug target site and a site where its side effect is expressed, which has a substituent cleavable with the enzyme and is activated due by cleaving the substituent. As an example of the drug target site, a respirato ry organ may be cited, while the heart may be sited as an example of the side effect expression site. As an example of the drug, a bronchodilator may be cited while a glicosidase (for example, .beta.-glucuronidase) may be cited a s an example of the enzyme. As an example of the substituent, a glycosyl group comprising a monosaccharide or an oligosaccharide may be cited. Use of the above enzyme makes it possible to lessen the side effect of a drug having a target site for exerting its effect which is different from a site where its side effect is expressed. |
| priorityDate |
2002-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |