http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2486139-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1da521f27baffc7ec053e6bcb29002e9
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-675
filingDate 2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8110a6c5752d5c7303336dddb214debf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cedcbdc08061836164e790116b319e5
publicationDate 2003-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2486139-A1
titleOfInvention Continuous process for the enantioselective catalytic hydrogenation of beta-ketoesters
abstract The present invention relates to a continuous process for the enantioselective catalytic hydrogenation of .beta.-ketoesters comprising providing a catalytic hydrogenation zone and maintaining it under conditions of temperature and pressure effective for the catalytic hydrogenation of .beta.-ketoesters; continuously supplying to the catalytic hydrogenation zone a substrate comprising a .beta.-ketoester to be hydrogenated, a catalyst effective for enantioselective hydrogenation of the .beta.-ketoester and hydrogen; contacting the substrate, the catalyst and the hydrogen in the hydrogenation zone for a residence time effective for at least partial enantioselective catalytic hydrogenation of the .beta.-ketoester; (d) continuously withdrawing from the hydrogenation zone a reaction product mixture comprising enantioselectively hydrogenated .beta.-ketoester, unreacted .beta.-ketoester, catalyst and hydrogen; (e) supplying the reaction product mixture to a separation zone and separating at least some of the enantioselectively hydrogenated .beta.-ketoester from the reaction product mixture; (f) withdrawing the separated enantioselectively hydrogenated .beta.-ketoester as product; and (g) optionally supplying at least part of the remaining material from the separation zone to the hydrogenation zone.
priorityDate 2002-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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