| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fdaffe64e0056ceff97698a913ed913 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18843
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-115 |
| filingDate |
2003-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8726dbb53db614482ac83dc3fbfe2b8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49feb2d7ad546e28385b5f33e87974a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8e7f945203c29f1765a3a065912c00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d8ce975552a74c6040459f48220fdd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e986f556ef6126034d39bedd382118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7e743f7ab863bd7bc087b8d914e6ac |
| publicationDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2484538-A1 |
| titleOfInvention |
Vectors with modified protease-dependent tropism |
| abstract |
It is intended to provide a cell fusion type vector having replicability with modified protease-dependent tropism. An M gene knockout virus vector encoding a modified F protein, in which the cleavage site of a paramyxovirus F protein has been modified into a sequence cleaved by another protease, is produced. When transferred into cells, this vector replicates genomic RNA carried thereby and thus extends the cell fusion type infection toward adjacent cells depending on the latter protease as described above but does not release any viral particles. Such a vector encoding an F protein cleaved by a protease the activity of which is enhanced due to cancer shows an effect of inhibiting caner growth in vivo. |
| priorityDate |
2002-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |