| abstract |
A drug containing, as the active ingredient, an antibody composition produce d with the use of cells tolerant to a lectin recognizing a sugar chain structu re in which an .alpha.-bond is formed between the 6-position of N- acetylglucosamine at the reducing end of an N-glycoside bond-type complex sugar chain and the 1-position of fucose. This drug is appropriate for patients suffering from Fc.gamma.RIIIa polymorphism who cannot be treated wi th a drug containing, as the active ingredient, an antibody composition produce d from cells not tolerant to a lectin recognizing a sugar chain structure in which an .alpha.-bond is formed between the 6-position of N-acetylglucosamin e at the reducing end of an N-glycoside bond-type complex sugar chain and the 1- position of fucose. |