| abstract |
The invention relates to novel 1-aza-bicyclic N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory. In a specific embodiment, the invention relates to a compound of the formula (I) (see formula I), in which R1 is a 1-azabicyclo[m.n.p]alkyl radical having 7 to 11 ring atoms, in which m and n are independently of one another 2 or 3, in which p is 1, 2 or 3, and where the bicycloalkyl radical is optionally substituted by (C1-C6)-alkyl, A is a bond, methylene, etc, E is divalent, 5- to 6-membered heteroaryl or benzenediyl, etc, R2 is 5- to 6-membered heteroaryl or phenyl, etc, and R3 is hydrogen or (C1-C6)-alkyl, or a salt, a solvate or a solvate of the salt thereof. |