| abstract |
The invention relates to novel, sustained-release IGF-I therapeutic compositions, a preparation and production method thereof and the use of sam e in the production of medicaments for the treatment and prevention of neurodegenerative diseases such as, among others, Alzheimer's disease or cerebellar ataxia. The inventive compositions take the form of microspheres having a size of less than 5 micrometres, among other characteristics, and subcutaneous implantation capsules. |