http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2477590-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2003-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f23a071fa01786f7842e8cef517c8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e9bcfc400a6ba4ee467987ee22e84bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5d5523d46838308949c12a2895b2d6f |
| publicationDate | 2003-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2477590-A1 |
| titleOfInvention | Sumo inhibitors |
| abstract | It is intended to provide a method of identifying a compound inhibiting the SUMO-conjugation of Tcf-4 by proteins of the protein inhibitor of activated STAT family (for example, PIASy, PIAS1, PIAS3 or PIASx.alpha.); compounds identified by this method; inhibitors for SUMO-conjugation of Tcf-4 by the PIAS family proteins and Tcf-4 SUMO-deconjugating agents; Tcf-4 transcriptional activity inhibitors comprising the above-described inhibitor s and/or SUMO-deconjugating agents; preventives and/or remedies for colon canc er comprising the above-described inhibitors and/or SUMO-deconjugating agents o r the transcriptional activity inhibitors; a method of inhibiting the transcriptional activity of Tcf-4 characterized by comprising inhibiting the SUMO-conjugation of Tcf-4 by the PIAS family protein and/or deconjugating SU MO- conjugated Tcf-4; and a method of preventing and/or treating colon cancer.</ SDOAB> |
| priorityDate | 2002-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.