| abstract |
A JNK inhibitor containing either a compound having an isoquinolinone skeleton, e.g., a compound represented by the formula (1) (wherein rings A and B each represents an optionally substituted benzene ring; X represents -O-, -N=, -NR3~-, or -CHR3~-; R2~ represents acyl, optionally esterified or thioesterified carboxy, optionally substituted carbamoyl, optionally substituted amino, etc.; the broken line represents a single bond or double bond; and R1~ represents hydrogen, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, etc.), or a salt of the compound. |