| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3aaa64837267ab15b721667f401817fe |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bcc85ae7bd6a4fa6996e205b05e5753
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0cf8c56a781da596612e1878063cf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e84224e55e426c9ec8403f32e9ca241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d8a253beba91b4f34fbf426791b0cd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64726796d33211d70f30be3cf6dad6fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_231e377661cd773a22ced62513979601
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7f41468ebd8159718f28bd9d80692ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc17db5457ce6f98233f90403647b90a |
| publicationDate |
2003-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2474469-A1 |
| titleOfInvention |
Chemical proteomics |
| abstract |
The invention relates to methods and reagents for identifying/isolating protein targets of chemical compounds (for example, drug candidates) using mass spectrometry. The invention provides a method for capturing and identifying proteins using tethered small-molecule probes. This technology also allows the market expansion of known drugs by finding new therapeutic targets; identification of the mechanism of toxicity of drug candidates or drugs which failed in the clinic; identification of new chemical tools for chemically-driven target validation; identification of new drug leads; and identification of the mechanism of action of drugs and drug candidates. A ke y advantage of the technology is that a single experiment can identify the numerous proteins which interact with a probe (or "bait"). |
| priorityDate |
2002-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |