| abstract |
The compounds of general formula (I) in which D signifies the Z-HET group, -HET being a 5-membered heterocycle such as oxadiazolone (II) or thiazolidine dione (III) of formulas (II and III) and -Z being chosen from the group consisting of - (CR1R2) n- and - (CR1 = CR2) n; where D signifies the group Z = HET, -Z- representing, with the heterocycle, a group -Z = HET of formula (IV) or (V) in which -Z = represents -CR1 =; are useful as inhibitors specific for non-pancreatic secreted phospholipase A2 (PLA2-snph) of group (II), in particular in therapy of inflammatory pathologies. |