| abstract |
A urea compound having a structure represented by the general formula [1] wa s newly found to have a pharmacological activity. The urea compound having a structure represented by the general formula [1] has excellent angiogenesis inhibitory activity. [1] [In the formula, A represents -(NR4)-, -(CR5R6)-, o r - O-; B represents alkylene or alkenylene; R1, R2, R4, R5, and R6 each represents hydrogen, alkyl, alkenyl, adantylalkyl, etc.; R3 represents aryl or unsaturated heterocycle; and X represents oxygen or sulfur.] |