| abstract |
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specif ic expression in normal adult tissue, and is aberrantly expressed in the cancer s listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic , prophylactic and/or therapeutic target for cancer. The 161P2F10B gene of fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passi ve immunization. |