| abstract |
The present invention concerns the field of urology. The invention provides a novel pharmaceutical composition, comprising a pharmaceutically effective combination of {i) a first compound selected from the group consisting of muscarinic receptor antagonists, 5.alpha.-reductase inhibitors, and .alpha.- adrenergic receptor antagonists, and precursors and pharmaceutically acceptable salts thereof, and {ii) a second compound selected from the group consisting of 5-HTla receptor agonists and antagonists, and precursors and pharmaceutically acceptable salts thereof, and optionally a pharmaceutically acceptable carrier or diluent therefor. There is also provided a method of therapeutical treatment of urinary disorder in a mammal, including man, comprising administering to said mammal, including man, in need of such treatment, a therapeutically effective amount of a composition according to the invention. |