| abstract |
The present invention relates to a compound of the formula: (see formula I) wherein G1 is a group of the formula: (see formula II) wherein ring B is an optionally substituted benzene ring, etc.; Q1 and Q2 are each a hydrogen atom, a halogen atom or alkyl; n is 0, 1, 2, 3 or 4; R1 is hydrogen atom, an optionally substituted alkyl, a cycloalkyl, or phenyl, etc.; Z1, Z2, Z3 and Z4 are each CH or N, provided that 3 or more of Z1, Z2, Z3 and Z4 should not be N at the same time; G2 is a hydrogen atom, -NR3R4, -OR5, etc., where R3 to R8 each is independently hydrogen atom, an optionally substituted alkyl, an alkenyl, an alkynyl, etc.; or a pharmaceutically acceptable salt thereof, which is useful for prophylaxis or treatment of inflammatory diseases such as arthritis. |