| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_294881271413951a95f284b588a68e66 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e73b83d9eebbec5671d8a5959e74739
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a7bf6cd5029795df7f7de674703cbaf |
| publicationDate |
2003-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2461094-A1 |
| titleOfInvention |
P300 histone acetylase inhibitor |
| abstract |
An inhibitor of p300 histone acetylase is isolated and identified from a hum an cDNA library. This inhibitor is a nuclear protein consisting of 855 amino ac id residues. This inhibitor binds to the cysteine/histidine rich domain of p300 and thus inhibits the transcriptional activation by p300. Moreover, it inhibits the transcriptional activity of p53, which is coactivated by p300, to thereby inhibit the cell cycle arrest depending on p53. |
| priorityDate |
2001-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |