| abstract |
A thiazolidine derivative represented by the general formula (I) [wherein X represents a substituent represented by the formula (I-a) or (I-b) (wherein m is 1 or 2; n is an integer of 1 to 5; X' represents hydrogen, etc.; Y' represents arylamino, heterocycle, etc.; A represents carbon or nitrogen; and Q represents aryl, etc.); Y represents methylene, sulfur, etc.; and Z represents hydrogen or cyano] and a pharmaceutically acceptable salt of the derivative. They have potent DPP-IV inhibitory activity and can hence be provided as, e.g. a preventive/remedy for diabetes or preventive/remedy for obesity. |