http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2459860-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66e14c7894b9649752ba93595b558634 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-2835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-4646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4644 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-46 |
| filingDate | 2003-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca7a238ecf5932dbffea367fbba71081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ee86320dcea476169347253d648be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af124ea4357b06044b6870c104d22cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8b366e6ab257d54d6a59df48d0bbe73 |
| publicationDate | 2004-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2459860-A1 |
| titleOfInvention | Allograft tissue purification process for cleaning bone |
| abstract | A method for producing a cleaned bone graft with osteoinductivity above 2.0 suitable for transplantation into a human. The first step is sonicating a bo ne graft in a nonionic detergent in an ultrasonic cleaner at a temperature ranging from about 33~- C to about 37~- C and for a time period ranging from 15 minutes to 2 hours effective to produce a cleaned bone graft essentially free from bone marrow. The bone graft is sonïcated in purified water in an ultrasonic cleaner at a temperature ranging from about 33-Q C to about 37' C a plurality of times to remove the detergent producing a cleaned bone graft. T he bone graft is then sonicated in hydrogen peroxide in an ultrasonic cleaner a t a temperature ranging from about 33~- C to about 37~- C for a time period ranging from 10 minutes to about 2 hours effective to retain osteoinductivit y of the bone graft and again sonicated in purified water in an ultrasonic cleaner at a temperature ranging from about 33~- C to about 3711 C a plurali ty of times to produce a cleaned bone graft. The final step is sonicating the bone graft in an alcohol at a temperature ranging from 33~- C to 37~- C for 30 minutes to 2 hours, all of the steps being effective to reduce any initially present viruses at least two logs and bacteria at least ten logs and the bon e graftis finally sonicated in purified water to remove the alcohol. |
| priorityDate | 2002-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.