| abstract |
It is intended to provide a novel low-molecular weight amine derivative havi ng a human .beta.-tryptase inhibitory activity which shows a high absorbability , a low toxicity and an extremely high selectivity, pharmaceutically acceptabl e salts thereof and drugs containing the same as the active ingredient. These drugs are efficacious as preventives/remedies for diseases in the onset and progress of which .beta.-tryptase seemingly participates, for example, respiratory diseases, allergic diseases, inflammatory intestinal diseases, hyperprolliferative skin diseases, vascular edema and rheumatoid arthritis.< /SDOAB> |