http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2455607-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d53094985a54e1cafd22f23d76be4007 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate | 2002-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e69b2738c07e8adab3a60ba702d00dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2638d0ff332a6bd9c83e999ed784415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e77b313e414efa17ac73b4e20d4671c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c2cf5af199576ae14c211c3e9cf4f70 |
| publicationDate | 2003-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2455607-A1 |
| titleOfInvention | Multiple controls for molecular genetic analyses |
| abstract | A method for constructing multiple nucleic acid sequences for use as positiv e controls in a genetic test is described. Compositions according to the invention including multiple nucleic acid sequences constructed as described are the optimal controls for simultaneously testing multiple variable nuclei c acid sequences at one or more DNA or RNA sites in a subject or subjects. Sequences according to the invention can be prepared chemically and/or by PC R amplification for use directly or after cloning and propagation. At the same time, some sequences can be PCR amplified and/or cloned directly from total genomic DNA obtained from an individual carrying the mutation or variant. Alternatively, the normal sequence to be changed can be cloned and then modified by site directed mutagenesis. Several single mutant or polymorphic sequences that together comprise a panel of multiple control sequences can b e added individually to single site tests or mixed together or ligated togethe r by further PCR or by cloning into vectors prior to use in individual or multiplex tests. Controls sequences constructed according to the invention c an be used when testing any genetically transmitted nucleic acid sequence by organizations testing quality assurance and by companies maintaining quality control of manufactured genetic test kits. |
| priorityDate | 2001-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 370.