| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26464a3a5f7400129d11161596bab004 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2517-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70517 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2002-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d2e20e0584ca1f6aa16d0b40c4ff93e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_669d6e37e3dc6ba0ed987e07f1d5efb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_477ca3f02b565c159fb1e404ac4aa0ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2981f4159393cbdf2905fab4de1dd5e4 |
| publicationDate |
2003-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2453928-A1 |
| titleOfInvention |
Cell and transgenic animal modelling human antigenic presentation and their uses |
| abstract |
The invention relates to an isolated animal cell comprising at least one transgene comprising at least one nucleotide sequence coding for at least a human polypeptide involved in recognition and / or activation antigenic by T cells, characterized in that said cell, or a descendant of said cell, expresses at least all or part of said one or more human polypeptide (s), and characterized in that the endogenous animal gene homologous coding for an animal polypeptide homologous to said human peptide is invalid. The invention also relates to the corresponding transgenic animal. The cell and the transgenic animal according to the invention can be works in a process for screening for compounds that modulate a reaction immune in humans. The invention also relates to the use of the cell according to the invention as a cell made autologous or tolerated by the immune system. |
| priorityDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |