| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16643
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-763
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 |
| filingDate |
2002-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02d2eecf9be92de64ba29bf3c6b47f92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b1ca32f1d574a4d74009702f3176bbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9af3cec00fa551bc0816518c22827c7b |
| publicationDate |
2010-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2447300-C |
| titleOfInvention |
Cell-specific replication-competent vector |
| abstract |
The present invention provides a method for constructing a vector which expresses and replicates a gene specifically to particular cells; a DNA having a gene expression regulatory activity used for its construction; and further, a treatment method comprising the steps of introducing said vector into particular living tissues or cells such as malignant tumors and the like, and said vector expressing and replicating a gene. A cell-specific replication-competent vector which does not act to normal cells in an adult body is constructed by obtaining a transcriptional initiation regulatory region of human calponin gene which is expressed specifically in cells; by linking it upstream of a viral replication-related gene; and by integrating it into a virus DNA. Said constructed cell-specific replication-competent vector is introduced into malignant tumor cells to selectively injure tumor cells or proliferating smooth muscle cells of tumor neovascular. |
| priorityDate |
2001-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |