| abstract |
An orally deliverable pharmaceutical composition is provided comprising a dr ug of low water solubility and a solvent liquid that comprises at least one pharmaceutically acceptable solvent, at least one pharmaceutically acceptabl e fatty acid and at least one pharmaceutically acceptable organic amine, where in (a) a substantial portion, for example at least about 15% by weight, of the drug is in dissolved or solubilized form in the solvent liquid, and (b) the fatty acid and the organic amine are present in total and relative amounts such that the composition is finely self-emulsifiable in simulated gastric fluid. |