abstract |
This invention provides a method for determining the antibody specificity profile in an individual. This specificity profile reveals the individual's immune response to multiple antigens and/or epitopes of autoantigens, allergens, graft antigens, etc. The antibody specificity profile is determin ed through the binding of patient samples comprising antibodies to the arrays. The array can comprises antigens and epitopes. The invention also provides t he means and methods for determining antigen or epitope specificity profiles th at can be used in the development of either generic and individualized diagnosi s and treatment for immune related diseases, including autoimmune disease, allergy and graft rejection. |