abstract |
A novel 1H-indazole compound having excellent JNK inhibitory activity. It is a compound represented by the following general formula (I), a salt thereof, o r a hydrate of either: (I) wherein R1 means C6-14 aromatic cyclic hydrocarbon group; R2, R4, and R5 each independently means hydrogen, halogeno, cyano, etc.; L means a single bond, C1-6 alkylene, etc.; X means a single bond, a group represented by -CO-NH- or -NH-CO-, etc.; and Y means C3-8 cycloalkyl, a C6-14 aromatic cyclic hydrocarbon group, a 5- to 14-membered aromatic heterocyclic group, etc. |