Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3130c25007b4859641ec5a22fc903139 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
filingDate |
2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f89f52fe64391629a52e3992a927454d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1fd1013af62d34488cc1caa1af915ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be2ecdca48dafd678be8ff87843eede0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f596d69c1901fad0b827e63dabc9c7ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec0ed14357e87fa636b3a2adc3640a68 |
publicationDate |
2004-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2428237-A1 |
titleOfInvention |
Process for the preparation of carbostyril derivatives |
abstract |
A process for preparing carbostyril derivatives such as aripiprazole is described. Dichlorophenylpiperazine or an acid addition salt thereof is reacted with a compound of formula X-C4H8-Y or X-C4H6-Y to produce a novel quaternary spiro ammonium salt intermediate which is optionally isolated and purified. The quaternary spiro ammonium salt intermediate is reacted with 7-hydroxydihydrocarboxystyryl to produce the carbostyril derivative. |
priorityDate |
2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |