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filingDate 2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f89f52fe64391629a52e3992a927454d
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publicationDate 2004-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2428237-A1
titleOfInvention Process for the preparation of carbostyril derivatives
abstract A process for preparing carbostyril derivatives such as aripiprazole is described. Dichlorophenylpiperazine or an acid addition salt thereof is reacted with a compound of formula X-C4H8-Y or X-C4H6-Y to produce a novel quaternary spiro ammonium salt intermediate which is optionally isolated and purified. The quaternary spiro ammonium salt intermediate is reacted with 7-hydroxydihydrocarboxystyryl to produce the carbostyril derivative.
priorityDate 2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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