| abstract |
Novel carbamate derivatives which are useful as drugs because of inhibiting activated blood coagulation factor X and thus exerting an anticoagulant effect. Compounds represented by the following general formula (1) or salts thereof: (1) wherein R1 represents an optionally substituted group represented by the following general formula (2), etc.: (2) (wherein Y1 represents CH=CH, etc.); the ring A represents an oxo-substituted nitrogen-containing heterocycle optionally further substituted; R2 represents hydrogen, optionally substituted C1-4 alkyl, etc.; R3 represents optionally substituted C1-4 alkyl, etc.; and Z represents an optionally substituted nitrogen containing heterocyclic group, etc. |