| abstract |
Indole derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof, and pharmaceutical compositions (particularly d opioid receptor agonist) containing the same: (I) wherein R1 is hydrogen, C1-5 alkyl, or the like; R2 is hydrogen, hydroxyl, or the like; R3 is hydrogen, hydroxyl, or the like; -Z- is a bridge having 2 to 5 carbon atoms; m is an integer of 0 to 3; n is an integer of 0 to 10; R4 and R5 are each fluoro, hydroxyl, or the like; R9 is hydrogen, C1-5 alkyl, or the like; and R10 and R11 may be united to form O- or the like. |