http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2422518-A1

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filingDate 2001-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2314d5c34f5afbf10042aad8ed40403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f02ee98e4f3b8d0606d68646a2b9421
publicationDate 2002-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2422518-A1
titleOfInvention Quadruplex dna and duplex probe systems
abstract A multiplex structure, such as a nucleic acid quadruplex, includes: a first strand containing a first sequence of nucleobases; a second strand containing a second sequence of nucleobases, wherein the second strand is associated with the first strand by Watson-Crick bonding; a third strand containing a third sequence of nucleobases; and a fourth strand containing a fourth sequence of nucleobases, wherein the fourth strand is associated with the second strand and the third strand by Watson-Crick bonding. Formation of the multiplex structure is promoted by monovalent cations (e.g., sodium and potassium), divalent cations, multivalent cations, intercalating agents and/or molecules known to bind within the minor grooves of nucleic acids. The multiplex structure and the process of forming it have diagnostic, therapeutic, prophylactic and nanoengineering applications.
priorityDate 2000-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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