http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2419851-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 |
| filingDate | 2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf36c473811ce0a8e0bfb667901575ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b5051805d84fc6f7f437cec399613b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78660f084a6958b09e6451c4a4ae42c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a99f4c686235ceeb584233b76e980d6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd6fc0c6029767d6bd48a8ad6ae513ec |
| publicationDate | 2002-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2419851-A1 |
| titleOfInvention | Genetic demonstration of requirement for nkx6.1, nkx2.2 and nkx6.2 in ventral neuron generation |
| abstract | This invention provides a method of converting a stem cell into a ventral neuron which comprises introducing into the stem cell a nucleic acid which expresses homeodomain transcription factor Nkx6.1 or Nkx6.2 protein in the stem cell so as to thereby convert the stem cell into the ventral neuron. Provided are methods of diagnosing a motor neuron degenerative disease in a subject. Also provides is a method of treating neuronal degeneration in a subjet which comprises implanting in diseased neural tissue of the subject a neural stem cell which is capable of expressing homeodomain Nkx6.1 or Nkx6.2 protein under conditions such that the stem cell is converted into a motor neuron after implantation, thereby treating neuronal degeneration in the subject. |
| priorityDate | 2000-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.