| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_850a17186ff51f03c607cf42a534a635 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate |
2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_139f92ceb4c60c39105fed8180160e40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6f97a4b7a60a1d2d75b6009429ef109
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8cb535ccd4b1f65175597b65a5eb2db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27c93045100278ce29e51bdf9c5ff449 |
| publicationDate |
2009-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2419665-C |
| titleOfInvention |
Novel 2-phenylpiperazine derivatives |
| abstract |
The present invention is to offer a useful novel compound as a tachykinin antagonist. This invention is a novel 2-phenylpiperazine derivative having an excellent tachykinin antagonistic action. A piperazine derivative of the present invention has an excellent tachykinin receptor antagonistic activity and exhibits a strong inhibitory action against tachykinin-induced increase of vascular permeability in vivo tests. Moreover, it shows a preferred transfer into blood and a long half-life in blood in pharmacokinetic tests of oral administration to rats or guinea pigs, and is very stable in blood plasma of various animals. Consequently, a piperazine derivative of the present invention is very useful as a novel tachykinin antagonist. |
| priorityDate |
2002-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |