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filingDate 2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d218bf80dc37d2f8771910b005224f71
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publicationDate 2003-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2419472-A1
titleOfInvention Sgk2 and sgk3 used as diagnostic and therapeutic targets
abstract The invention relates to the use of a substance, which detects sgk2 and/or sgk3, for diagnosing diseases connected with a disturbance of ion channel activity, in particular, sodium and/or potassium channels. The invention also relates to the use of an active ingredient for treating the aforementioned diseases, said active ingredient influencing the expression and/or the function of sgk2 and/or sgk3 and regulating the elimination of Na+ and/or K+ as a result. The preferred active ingredients are staurosporine and/or chelerythrine.
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