http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2417119-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
filingDate 2001-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_935cc64d4e7164e3c70d737c35106c7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df0434c5628f394583ebcbc8cda11b1d
publicationDate 2003-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2417119-A1
titleOfInvention Method for the enantioselective reduction of 8-chloro-6-oxo-octanoic acid alkyl esters
abstract The invention relates to a method for the production of (R)- or (S)-8-chloro -6- hydroxyoctanoic acid alkyl esters of general formula (R)-II or (S)-II, where R = C1-4 alkyl, from 8-chloro-6-oxo-octanoic acid alkyl esters of general formula (I), where R has the above meaning. The production of the desired enantiomers is achieved biocatalytically by means of an enantioselective reaction, whereby the strains Mucor racemosus for (S)-II compounds and Geotrichum candidum for (R)-II compounds are used. The esters thus obtained can be sterospecifically converted to (R)-.alpha.-lipoic acid by conventiona l methodology.
priorityDate 2000-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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