| abstract |
Pyrrole derivatives represented by the following formula or pharmaceutically acceptable salts of these: wherein ring Z represents an optionally substituted pyrrole ring, etc.; W2 represents -CO-, -SO2-, optionally substituted C1-4 alkylene, etc.; Ar2 represents optionally substituted aryl, etc.; and W1 and Ar1 mean the following (1) or (2) W1 represents optionally substituted C1-4 alkylene, etc. and Ar1 represents dicyclic heteroaryl having one to four, optionally substituted nitrogen atoms as ring-forming atoms, W1 represents optionally substituted C2-5 alkylene, optionally substituted C2-5 alkenylene, etc. and Ar1 represents an aryl or monocyclic heteroaryl group substituted by carboxyl, alkoxycarbonyl, etc. in a position ortho or meta to the W1. They are useful as a medicine such as a fibroid inhibitor for organs or tissues. |