| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-105 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38b8d4c9b12027289457fc8f16bd8245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a97c0722805fe2de84dda4c4122e998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d63a59933bb2380852398513b5b170
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f85decd3aeafa90c3c86884c7797a86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70a43fd1c3513b1c0b32b377e346d363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a9b30d48d1bf15087ac43449e2ccc13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b36c20552eceb892c87936977aa8904 |
| publicationDate |
2002-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2415960-A1 |
| titleOfInvention |
Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| abstract |
The invention provides peptide synthons having protected functional groups for attachment of desired moieties (e.g. functional molecules or probes). Also provided are peptide conjugates prepared from such synthons, and synthon and conjugate preparation methods including procedures for identifying optimum probe attachment sites. Biosensors are provided having functional molecules that can locate and bind to specific biomolecules within living cells. Biosensors can detect chemical and physiological changes in those biomolecules as living cells are moving, metabolizing and reacting to its environment. Methods are included for detecting GTP activation of a Pho GTP are protein using polypeptide biosensors. When the biosensor binds GTP-activated Rho GTPase protein, an environmentally sensitive dye emits a signal of a different lifetime, intensity or wavelength than when not bound. New fluorophores whose fluorescence responds to environmental changes are also provided that have improved detection and attachment properties, and that can be used in living cells, or in vitro. |
| priorityDate |
2000-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |