| abstract |
This disclosure relates to the use of .alpha.,.alpha.-dibromo-.alpha.- chloroacetophenone compounds as intermediates for the preparation of aromati c carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2- trifluoroethoxy)-.alpha.,.alpha.-dibromo-.alpha.-chloro-acetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical. |