| abstract |
Disclosed are compositions for treating tumors and the use of such compositions. Disclosed compositions enhance the uptake of immunocytokines into tumors, and are based on a combination of an immunocytokine with an immunocytokine uptake enhancing agent. The immune uptake enhancing agent is taxol, docetaxel, 10-deacetyl Baccatin III, cyclophosphamid or carboplatin, and can be administered to a mammal prior to the immunokine. Disclosed compositions are particularly useful for reducing tumor size and metastasis in a mammal. |