| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50fbea928a51ed6422393cb790f1e5c9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 |
| filingDate |
2001-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14f6c06d981f3a445249e92cf6925be2 |
| publicationDate |
2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2411914-A1 |
| titleOfInvention |
Method of controlling differentiation of embryonic stem (es) cells by culturing es cells in the presence of bmp-2 pathway antagonists |
| abstract |
ES cells have a natural tendency to differentiate into cells resembling thos e of the extra-embryonic endodermal lineages in the early human embryo. Applicants have found that culturing ES cells in the presence of direct and/ or indirect antagonists of the BMP-mediated default pathway of extra-embryonic endoderm differentiation will prevent ES cells from proceeding along this pathway. |
| priorityDate |
2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |