http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2411186-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_588f4799eeda38576f3d4784cef85ded |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
| filingDate | 2002-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7451ebfbe4ba89106a8329d5d3f4fdd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2149a5a203cbc5c410964512250cb2a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dae9aa27358341b1c641e69e89bfa73 |
| publicationDate | 2003-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2411186-A1 |
| titleOfInvention | Induction of tolerance to a therapeutic polypeptide |
| abstract | Liver-directed gene transfer can induce immunological tolerance to a polypeptide associated with the expression of a therapeutic nucleic acid Hepatic expression of a transgene induces tolerance to the expression product of the transgene, or to post-translational product related to transgene expression, thereby ameliorating or eliminating the immune responses associated with gene therapy and protein replacement, respectively, independent of the genetic background of the subject. |
| priorityDate | 2001-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.