| abstract |
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula (I) wherein one of X, Y or Z is independently -S-,-0- CH2- or >N-R6, the others are -CH2-; m is an integer from 0 to 3 inclusive; n is an integer from 1 to 6 inclusive; R4 is (C1-6)-alkyl; R5 is independently in each occurrence (C1-6)-alkyl, (C1-6)-alkenyl, (C1-6)- alkynyl or cycloalkyl; and R1, R2, and R3 are hydrogen or specified substituents. These compounds are useful for treating diseases associated with smooth muscle disorders. |