Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8afdfc8f7b80752223680a5da978c42b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate |
2001-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab8f0f62368147d99fd05d6b58e8689c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25633b494d8e115550e08e8f1d6064c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_788095a05cb224afdf99c347964f3db7 |
publicationDate |
2001-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2409355-A1 |
titleOfInvention |
Neuroprotective and anti-proliferative compounds |
abstract |
This invention features ring-substituted pyrrolo-.beta.-carboline derivatives and ring-substitution and structural derivatives of 3-(1H-indol-3-yl)-1H-pyrrole-2,5-dione of formulas (I - III), which are useful as neuroprotective and anti-proliferative compounds. Also disclosed are methods for the preparation of these compounds, selected biological profiles and uses of these compounds in the treatment of various neurodegenerative and inflammatory diseases of the human nervous system and in the treatment of various other proliferative disorders characterized by loss of growth or cellular differentiation control including, but not limited to, cancer and inflammation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2420780-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005014584-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112996521-A |
priorityDate |
2000-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |