http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2408148-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a60f2356a531632d07da307ed7287692 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-46 |
| filingDate | 2001-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f7d7cd6fae64baa733c665100382f1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c6956f01700166b1fe760aae7ab2c0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad924ef286ce03df3517adc96a506d8 |
| publicationDate | 2001-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2408148-A1 |
| titleOfInvention | Assay for detecting, measuring and monitoring the activities and concentrations of proteins and methods of use thereof |
| abstract | An assay for detecting, measuring, or monitoring the activity or concentrati on of at least two proteins that have similar or overlapping properties is disclosed. The assay comprises first determining the sensitivity coefficient s of the substrates for each of the proteins. This method may be used for detecting, measuring, or monitoring the activity and concentration of AChE, BChE, or both in a test sample which test sample may be whole and unprocesse d blood or tissue. Also disclosed are methods of using the assay to detect a subject's exposure to an agent which affects cholinesterase, determine the efficacy or progress of a treatment, determine the amount of protection provided against exposure to an agent which affects cholinesterase, or both, screen a subject for having a drug sensitivity or particular disease, detect a change in red blood cell count of a subject, determine whether a candidate compound affects cholinesterase. Also disclosed are devices and kits for detecting, measuring, or monitoring the activities and concentrations of ACh E, BchE, or both. Figure (1) is a graph which illustrates that AChE is inhibite d by small concentrations of 2-PAm, on oxime and part of the United States Army's current treatment regime for organophosphate and pesticide poisoning, while BChE is relatively unaffected. |
| priorityDate | 2000-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.