http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2406847-C

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filingDate 2001-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19bd00b8446163d0c6d7931c6e1967c5
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publicationDate 2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2406847-C
titleOfInvention Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols
abstract An efficient method for the synthesis of aminosterol compounds such as squalamine and compound 1436 is de-scribed. A method of the invention provides for regioselective oxidation and regioselective sulfonation of a fused ring system. The fused ring base can be, for example, a steroid ring base. The aminosterol compounds are effective as, among others, antibiotics, antiangiogenic agents and NHE3 inhibitors.
priorityDate 2000-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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