Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a7d918fd05361ab10fb2ab248a2e310 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
filingDate |
2001-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19bd00b8446163d0c6d7931c6e1967c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d34f4d27300b8cce9990d6eb8a5e9636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6e9b4f7e62ac5d3987784bcc2e9a257 |
publicationDate |
2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2406847-C |
titleOfInvention |
Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols |
abstract |
An efficient method for the synthesis of aminosterol compounds such as squalamine and compound 1436 is de-scribed. A method of the invention provides for regioselective oxidation and regioselective sulfonation of a fused ring system. The fused ring base can be, for example, a steroid ring base. The aminosterol compounds are effective as, among others, antibiotics, antiangiogenic agents and NHE3 inhibitors. |
priorityDate |
2000-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |