abstract |
This invention is directed to 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives useful as .delta.-opioid or ยต-opioid receptor modulators. Depending on their agonist or antagonist effect, the compounds are useful analgesics, immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases. |