| abstract |
The present invention relates to a novel calcium phosphate artificial bone promotive of biocompatible osteoanagenesis, which comprises an ordinary calcium phosphate bone cement and a linear polyphosphate. The linear polyphosphate of the calcium phosphate artificial bone comprises 3-200 orthophosphate molecules and is used in an amount of 0.001-0.05 % by weight based on the total weight of the calcium phosphate artificial bone. The polyphosphate-containing artificial bone of the present invention is non-toxic to the body and chemically stable, and economically favorable in terms of production cost with superior biodegradability. Thus, the polyphosphate-containing artificial bone of the present invention can replace as osteoconductive and osteoinductive, biodegradable substitute for a conventional bone cements,allografts and autografts which are used in the treatment of defects and fractures in every bone of the body, the cure of osteoporous, the fillers of implant for dental surgery, the bone substitute for plastic surgery, the substitution of defected bones in the operation on joints, including hip-joint, knee-joint and shoulder joint, and the operation on the vertabra. |